RF ablation

MRI Accurately Visualizes RF Ablation Delivery Targeted to MRI-Defined Arrhythmia Substrates in the Left Ventricle

MRI Accurately Visualizes RF Ablation Delivery Targeted to MRI-Defined Arrhythmia Substrates in the Left Ventricle

MRI Accurately Visualizes RF Ablation Delivery Targeted to MRI-Defined Arrhythmia Substrates in the Left Ventricle 789 444 IEEE Transactions on Biomedical Engineering (TBME)
This study integrates MR imaging with conventional cardiac ablation guidance, investigating MR visualization of therapeutic RF lesions at arrhythmogenic substrates. High MRI accuracy suggests potential utility alongside clinical ablation endpoints. read more

MRI-Guided Cardiac RF Ablation for Comparing MRI Characteristics of Acute Lesions and Associated Electrophysiologic Voltage Reductions

MRI-Guided Cardiac RF Ablation for Comparing MRI Characteristics of Acute Lesions and Associated Electrophysiologic Voltage Reductions 2560 1427 IEEE Transactions on Biomedical Engineering (TBME)
This study characterizes permanent and transient injury caused by cardiac RF ablation in a preclinical model. Native-contrast MRI features of ablation were investigated in relation to catheter-based electrophysiologic (EP) signals inherently co-registered within the same coordinate frame, and histologically validated. Specifically, we show that bipolar voltage was reduced in the presence of both the permanent T1-derived RF lesion and transient T2-derived edema. These results suggest that these regions are distinct in native-contrast MRI, but not differentiable using bipolar voltage. Intraprocedural MRI visualization distinguishing transient and permanent injury could guide creation of more complete durable RF ablations, reducing arrhythmia recurrence. read more